Evidence

We don't believe in "black boxes". Our technology, statistical methods, and outputs have all been through rigorous peer-review, making our platform and our evidence trustable with even the rarest and most complex patients.

 

Peer-Reviewed Methods

The following are studies that detail the specific methods Atropos uses to deliver rapid real-world evidence

Using Aggregate Patient Data at the Bedside via an On-Demand Consultation Service.

September 2021 Callahan A, Gombar S, Cahan E, Jung K, Steinberg E, Polony V, Morse K, Tibshirani R, Hastie T, Harrington R, Shah N.

 

ACE: the Advanced Cohort Engine for searching longitudinal patient records.

March 2021 Callahan A, Polony V, Posada J, Banda J, Gombar S, Shah N. PMID: 33712854

 

It is Time to Learn from Patients Like Mine.

March 2019. Gombar S, Callahan A, Califf R, Harrington R, Shah NH. PMID: 31304364

 

Performing an Informatics Consult: Methods and Challenges.

March 2018. Schuler A, Callahan A, Jung K, Shah NH. PMID: 29396125

 

A 'Green Button' For Using Aggregate Patient Data at the Point of Care.

July 2014. Longhurst CA, Harrington RA, Shah NH. PMID: 25006150

Peer-Reviewed Literature Generated by Atropos Technology

In each of the following peer-reviewed journal articles, the entirety of the analyzes presented was derived from Prognostograms, along with commentary from the ordering provider team

Association of Systemic Diseases With Surgical Treatment for Obstructive Sleep Apnea Compared With Continuous Positive Airway Pressure.

Badr Ibrahim et. to the. JAMA Otolaryngol Head Neck Surg. Published online January 2021

 

Step-down from IV to oral therapy in patients with bacteremia due to Enterobacteriaceae: fluoroquinolones (FQ) vs. ß-lactams (BL) or trimethoprim-sulfamethoxazole (TMP-SMX).

Lina Meng et. to the. Open Forum Infectious Diseases, Volume 6, October 2019

 

Real-world efficacy of bone modifying agents (BMAs) in patients with breast cancer (BC) treated in an academic health system: Use of the "green button".

Yasmin Karimini et. Al. Journal of Clinical Oncology 2019 37:15

 

Cardiovascular Safety of Mexiletine as Therapy for Myotonia In Patients with Myotonic Dystrophy.

June Rhee et. to the. J Am Coll Cardiol. 2019 Mar. 73: 474

 
 

Associations of Tinnitus Incidence with Use of Tumor Necrosis Factor-Alpha Inhibitors among Patients with Autoimmune Conditions

Nirvikalpa Natarajan et al. J. Clin Med. 2023 Mar 1.